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Optical and electrochemical aptasensors for the detection of amphenicols.

Department of nutrition, Varastegan institute of Medical sciences, Mashhad, Iran; Department of Food Hygiene and Aquaculture, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran. Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Food Hygiene and Aquaculture, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: taghdisihm@mums.ac.ir. Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: alibolandim@mums.ac.ir.

Biosensors & bioelectronics. 2018;:137-152
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Abstract

Various methods have been introduced to detect amphenicols in biological samples. However, because of some problems involved in conventional methods, such as time-consuming processes, expensive equipment, and high consumption of reagents, novel strategies for the detection and quantitative determination of amphenicols are required. Aptamer-based biosensors with unique recognition features have gained much attention because of their rapid response, high specificity, and simple fabrication. In this study, we summarized the optical and electrochemical amphenicol aptasensors with a focus on the recent advancements and modern approaches in amphenicol aptasensors to provide readers with an inclusive understanding of their improvement.

Methodological quality

Publication Type : Review

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MeSH terms : Anti-Bacterial Agents